The AJR group
Dr Carole Bataille
I did my undergraduate in Organic Chemistry at the University of Rouen and obtained my PhD on permanganate oxidative cyclisation under the supervision of Dr R.C.D. Brown at the University of Southampton. I then undertook two consecutive post-doctoral positions with Professor T.J. Donohoe on tethered aminohydroxylation methodology and with Dr J.M. Brown on resolution of stereolabile biaryl ligands using novel chiral dienes at the Chemistry Research Laboratory, Oxford.
I previously worked as a senior post-doctoral researcher in the AJR group and with Professor S.G. Davies, at Oxford. I had the opportunity to work on a range of medicinal chemistry projects from synthesizing novel PIM kinase inhibitors used in the treatment of cancer, to anti-viral agents against Hepatitis C virus as well as novel compounds used in the proliferation of stem cells and their selective differentiation.
I am currently working on a collaborative project with Professor TH Rabbitts funded by Leukaemia and Lymphoma Research on the synthesis of novel chiral small molecules, used in protein-protein interaction to prevent, proliferation of cancer cells via a fragment-based approach and in silico methods using inhibition antibody fragments as structured templates.