Publications
2017
Venturi, E., Lindsay, C., Lotteau, S., Yang, Z., Steer, E., Witschas, K., Wilson, A. D., Wickens, J. R., Russell, A. J., Steele, D., Calaghan, S., and Sitsapesan, R. Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform. British Journal of Pharmacology, 2017. doi: 10.1111/bph.14136.
Tempone, A.G.; Ferreira, D.D.; Lima L.M.; Silva, T.A.C.; Borborema, S.E.T.; Reima, J.Q.; Galuppo, M.K.; Guerra, J.M.; Russell, A.J.; Wynne, G.M.; Lai, R.Y.L.; Cadelis, M.M.; Copp, B.R. Efficacy of a series of alpha-pyronederivatives against Leishmania (L.) infantum and Trypanosoma cruzi. European Journal of Medicinal Chemistry 2017, 139, 947-960.
Kerr, A.G.; Tam, L.C.S.; Hale, A.B.; Cioroch, M.; Douglas, G.; Agkatsev, S.; Hibbitt, O.; Mason, J.; Holt-Martyn, J.; Bataille, C.J.R.; Wynne, G.M.; Channon, K.M.; Russell, A.J. and Wade-Martins, R. A genomic DNA reporter screen identifies squalene synthase inhibitors which act cooperatively with statins to upregulate the low-density lipoprotein receptor. Journal of Pharmacology and Experimental Therapeutics 2017, 361 (3), 417-428.
Partridge, FA.; Murphy, EA.; Willis, NJ.; Bataille, CJR.; Forman, R.; Heyer-Chauhan, N.; Marinič, B.; Sowood, DJC.; Wynne, GM.; Else, KJ.; Russell, AJ.; Sattelle, DB. Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo. PLoS Negl Trop Dis 11(2): e0005359. doi:10.1371/ journal.pntd.0005359.
Bataille, CJR.; Brennan, MB.; Byrne, S.; Davies, SG.; Durbin, M.; Fedorov, O.; Huber, KVM,; Jones, AM.; Knapp, S.; Liu, G.; Nadali, A.; Quevedoa, CE.; Russell, AJ.; Walker, RG.; Westwood, R.; Wynne, GW. Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Bioorganic and Medicinal Chemistry, 2017. http://dx.doi.org/10.1016/j.bmc.2017.02.056
2016
Russell, A.J. and Silpa, L. Chemical-Induced Naive Pluripotency. Cell Chemical Biology, 2016, 23, 532-534. doi:10.1016/j.chembiol.2016.05.002
McIntyre, A.; Hulikova, A.; Ledaki, I.; Snell, C.; Singleton, D.; Steers, G.; Seden, P.; Jones, D.; Bridges, E.; Winfield, S.; Li, J.L.; Russell, A.; Switch, P.; Harris, A.L. Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth. Cancer Res 2016, 76, 3744–55
Davies, S. G.; Goddard, E, C.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Thomson, J. E.; Withey, J. M. Strategies for the construction of morphinan alkaloid AB-rings: regioselective Friedel-Crafts-type cyclisations of γ-aryl-β-benzoylamido acids with asymmetrically substituted γ-aryl rings. Tetrahedron: Asymmetry 2016, 27, 274.
Clunie-O’Connor, C.; Smits, A.M.; Antoniades, C.; Russell, A.J.; Yellon, D.M.; Goumans, M-J.; Riley, P.R. The Derivation of Primary Human Epicardium-Derived Cells. Curren. Protoc. Stem Cell Biol. 2016, 35: 2C.5.1 - 2C.5.x.
Zervou, S.; Whittington, H.J.; Russell, A.J. and Lygate, C.A. Augmentation of creatine in the heart. Mini-reviews in Medicinal Chemistry. 2016, 16, 19-28.
2015
Guiraud, S.; Squire, S. E.; Edwards, B.; Chen, H.; Burns, D. T.; Shah, N.; Babbs, A.; Davies, S. G.; Wynne, G. M.; Russell, A. J.; Elsey, D.; Wilson, F. X.; Tinsley, J. M.; Davies, K. E.
Second-generation compound for the modulation of utrophin in the therapy of DMD.
Hum. Mol. Genet. 2015, doi: 10.1093/hmg/ddv154
Brennan, M.; Csatayová, K.; Davies, S. G.; Fletcher, A. M.; Green, W. D.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.
Syntheses of dihydroconduramines (±)-B-1, (±)-E-1 and (±)-F-1 via diastereoselective epoxidation of N-protected 4-aminocyclohex-2-en-1-ols.
J. Org. Chem. 2015, doi: 10.1021/acs.joc.5b00716
Taylor, L.; Christou, I.; Kapellos, T. S.; Buchan, A.; Brodermann, M. H.; Gianella-Borradori, M.; Russell, A.; Iqbal, A. J.; Greaves, D. R.
Primary macrophage chemotaxis induced by cannabinoid receptor 2 agonists occurs independently of the CB2 receptor.
Scientific Rep. 2015, doi: 10.1038/srep10682
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Davies, S. G.; Kennewell, P. D.; Russell, A. J.; Seden, P. T.; Westwood, R.; Wynne, G. M.
Stemistry: The Control of Stem Cells in Situ Using Chemistry.
J. Med. Chem. 2015, 58, 2863-2894.
Davies, S. G.; Goddard, E. C.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.
Enantiopure 3-amino substituted 1-indanones, 1-tetralones and 1-benzosuberones via Friedel-Crafts cyclisation of ω-aryl-β-benzamido acids.
Synlett 2015, doi:10.1055/s-0034-1380675
Brennan, M. B.; Davies, S. G.; Fletcher, A. M.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.
Epoxidation of trans-4-aminocyclohex-2-en-1-ol derivatives: competition of hydroxyl-directed and ammonium-directed pathways.
Aust. J. Chem. 2015, 68, 610-621.
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Gianella-Borradori, M.; Christou, I.; Bataille, C. J. R.; Cross, R. L.; Wynne, G. M.; Greaves, D. R.; Russell, A. J.
Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists.
Bioorg. Med. Chem. 2015, 23, 241-263.
2014
Laurieri, N.; Kawamura, A.; Westwood, I. M.; Varney, A.; Morris, E.; Russell, A. J.; Stanley, L. A.; Sim, E.
Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding.
BMC Pharmacol. Toxicol. 2014, 15, 68.
Abuhammad, A.; Fullam, E.; Bhakta, S.; Russell, A. J.; Morris, G. M.; Finn, P. W.; Sim, E.
Exploration of Piperidinols as Potential Antitubercular Agents.
Molecules 2014, 19, 16274–16290.
Egleton, J. E.; Thinnes, C. C.; Seden, P. T.; Laurieri, N.; Lee, S. P.; Hadavizadeh, K. S.; Measures, A. R.; Jones, A. M.; Thompson, S.; Varney, A.; Wynne, G. M.; Ryan, A.; Sim, E.; Russell, A. J.
Structure-activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1.
Bioorg. Med. Chem. 2014, 22, 3030–3054.
Laurieri, N.; Dairou, J.; Egleton, J. E.; Stanley, L. A.; Russell, A. J.; Dupret, J. M.; Sim, E.; Rodrigues-Lima, F.
From Arylamine N-Acetyltransferase to Folate-Dependent Acetyl CoA Hydrolase: Impact of Folic Acid on the Activity of (HUMAN)NAT1 and Its Homologue (MOUSE)NAT2.
PLoS One 2014, 9, e96370.
2013
Lufino, M. M. P.; Silva, A. M.; Németh, A. H.; Alegre-Abarrategui J.; Russell A. J.; Wade-Martins, R. A
Novel Genomic DNA Reporter Model of Friedreich’s Ataxia Carrying Expanded GAA Repeats Identifies A New Frataxin Up-regulating Compound.
Human Mol. Genet. 2013, 22, 5173–5187.
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Russell, A. J.
Regenerative Medicinal Chemistry: The in Situ Control of Stem Cells.
ACS Med. Chem. Lett. 2013, 4, 365–368.
Claridge, T. D. W.; Davies, S. G.; Kruchinin, D.; Odell, B.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.; Toms, S. M.
Solution phase structures of enantiopure and racemic lithium N-benzyl-N-(α-methylbenzyl)amide in THF: Low temperature Li and N NMR spectroscopic studies.
Tetrahedron Asymmetry 2013, 24, 947–952.
Laurieri, N.; Egleton, J.E.; Varney, A.; Thinnes, C. C.; Quevedo, C. E.; Seden, P.T.; Thompson, S.; Rodrigues-Lima, F.; Dairou, J.; Dupret, J.-M.; Russell, A. J.; Sim, E.
A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1.
PLoS One 2013, 8, e70600.
Fullam, E.; Talbot, J.; Abuhammed, A.; Westwood, I.; Davies, S. G.; Russell, A. J.; Sim, E.
Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
Bioorg. Med. Chem. Lett. 2013, 23, 2759–2764.
Hewings, D. S.; Fedorov, O.; Filippakopoulos, P.; Martin, S.; Picaud, S.; Tumber, A.; Wells, C.; Olcina, M. M.); Freeman, K.; Gill, A.; Ritchie, A. J.; Sheppard, D. W.; Russell, A. J.; Hammond, E. M.; Knapp, S.; Brennan, P. E.; Conway, S. J.
Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands.
J. Med. Chem. 2013, 56, 3217–3227.
2012
Abuhammad, A.; Fullam, E.; Lowe, E. D.; Staunton, D.; Kawamura, A.; Westwood, I. M.; Bhakta, S.; Garner, A. C.; Wilson, D. L.; Seden, P. T.; Davies, S. G.; Russell, A. J.; Garman, E. F.; Sim, E.
Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages.
PLoS One 2012, 7, e52790.
Davies, S. G.; Fletcher, A. M.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Taylor, R. J.; Thomson, A. D.; Thomson, J. E.
Polysubstituted Piperidines via Iodolactonization: Application to the Asymmetric Synthesis of (+)-Pseudodistomin D.
Org. Lett. 2012, 14, 1672–1675.
Davies, S. G.; Fletcher, A. M.; Hughes, D. G.; Lee, J. A.; Price, P. D.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Thomson, J. E.; Williams, O. M. H.
Asymmetric synthesis of piperidines and octahydroindolizines using a one-pot ring-closure/N-debenzylation procedure.
Tetrahedron 2011, 67, 9975–9992.
Li, J. L.; Sainson, R. C. A.; Oon, C. E.; Turley, H.; Leek, R.; Sheldon, H.; Bridges, E.; Shi, W.; Snell, C.; Bowden, E. T.; Wu, H. R.; Chowdhury, P. S.; Russell, A. J.; Montgomery, C. P.; Poulsom, R. and Harris, A. L.
DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo.
Cancer Res. 2011, 71, 6073–6083.
Csatayova, K.; Davies, S. G.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.; Wilson, D. L.
Highly Diastereoselective and Stereodivergent Dihydroxylations of Acyclic Allylic Amines: Application to the Asymmetric Synthesis of 3,6-Dideoxy-3-amino-L-talose.
Org. Lett. 2011, 13, 2606–2609.
Westwood, I. M.; Kawamura, A.; Russell, A. J.; Sandy, J.; Davies S. G. and Sim, E.
Novel Small-Molecule Inhibitors of Arylamine N-Acetyltransferases: Drug Discovery by High Throughput Screening.
Combi. Chem. High Throughput Screening 2011, 14, 117–124.
Fullam, E.; Abuhammad, A.; Wilson, D. L.; Davies, S. G.; Russell, A. J. and Sim, E.
Analysis of beta-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase.
Bioorg. Med. Chem. Lett. 2011, 21, 1185–1190.
Abraham, E.; Claridge, T. D. W.; Davies, S. G.; Odell, B.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Smith, L. J.; Storr, H. R.; Sweet, M. J.; Thompson, A. L.; Thomson, J. E.; Tranter, G. E.; Watkin, D. J.
A systematic study of the solid state and solution phase conformational preferences of beta-peptides derived from C(3)-alkyl substituted transpentacin derivatives.
Tetrahedron: Asymmetry 2011, 22, 69–100.
2010
Laurieri, N.; Crawford, M. H. J.; Kawamura, A.; Westwood, I. M.; Robinson, J.; Fletcher, A. M.; Davies, S. G.; Sim, E. and Russell, A. J.
Small Molecule Colorimetric Probes for Specific Detection of Human Arylamine N-Acetyltransferase 1, a Potential Breast Cancer Biomarker.
J. Am. Chem. Soc. 2010, 132, 3238–3239.
Csatayova, K.; Davies, S. G.; Lee, J. A.; Ling, K. B.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.
Chemo- and diastereoselective cyclopropanation of allylic amines and carbamates.
Tetrahedron 2010, 66, 8420–8440.
Davies, S. G.; Ling, K. B.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.; Woods, P. A.
The stereodivergent aziridination of allylic carbamates, amides and sulphonamides.
Tetrahedron 2010, 66, 6806–6813.
Csatayova, K.; Davies, S. G.; Lee, J. A.; Ling, K. B.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.
Syntheses of trans-SCH-A and cis-SCH-A via a Stereodivergent Cyclopropanation Protocol.
Org. Lett. 2010, 12, 3152–3155.
Abraham, E.; Bailey, C. W.; Claridge, T. D. W.; Davies, S. G.; Ling, K. B.; Odell, B.; Rees, T. L.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Smith, L. J.; Storr, H. R.; Sweet, M. J.; Thompson, A. L.; Thomson, J. E.; Tranter, G. E.; Watkin, D. J.
A systematic study of the solid state and solution phase conformational preferences of beta-peptides derived from transpentacin.
Tetrahedron: Asymmetry 2010, 21, 1797–1815.
Cresswell, A. J.; Davies, S. G.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.; Tyte, M. J.
beta-Fluoroamphetamines via the Stereoselective Synthesis of Benzylic Fluorides.
Org. Lett. 2010, 12, 2936–2939.
Bentley, S. A.; Davies, S. G.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.; Toms, S. M.
Conjugate addition of lithium N-tert-butyldimethylsilyloxy-N-(alpha-methylbenzyl)amide: asymmetric synthesis of beta(2,2,3)-trisubstituted amino acids.
Tetrahedron 2010, 66, 4604–4620.
Westwood, I. M.; Bhakta, S.; Russell, A. J.; Fullam, E.; Anderton, M. C.; Kawamura, A.; Mulvaney, A. W.; Vickers, R. J.; Bhowruth, V.; Besra, G. S.; Lalvani, A.; Davies, S. G. and Sim, E.
Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.
Protein & Cell 2010, 1, 82-95.
Davies, S. G.; Hughes, D. G.; Price, P. D.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Thomson, J. E. And Williams, O. M. H.
Asymmetric Synthesis of Piperidines and Octahydroindolizines.
Synlett 2010, 567–570.
Bagal, S. K.; Davies, S. G.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Scott, P. M. and Thomson, J. E.
An Oxidation and Ring Contraction Approach to the Synthesis of (+/-)-1-Deoxynojirimycin and (+/-)-1-Deoxyaltronojirimycin.
Org. Lett. 2010, 12, 136–139.
2009
Bond, C. W.; Cresswell, A. J.; Davies, S. G.; Fletcher, A. M.; Kurosawa, W.; Lee, J. A.; Roberts, P. M.; Russell, A. J.; Smith, A. D. and Thomson, J. E.
Ammonium-Directed Oxidation of Cyclic Allylic and Homoallylic Amines.
J. Org. Chem. 2009, 74, 6735–6748.
Soncin, F.; Mohamet, L.; Eckardt, D.; Ritson, S.; Eastham, A. M.; Spencer, H.; Bobola, N.; Russell, A. J.; Davies, S. G.; Kemler, R.; Merry, C. L. R. and Ward, C. M.
Abrogation of E-cadherin mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal.
Stem Cells 2009, 27, 2069–2080.
Wilkinson, R. N.; Gering, M.; Russell, A. J.; Davies, S. G.; Kimelman, D. and Patient, R.
Hedgehog and Bmp Polarize Hematopoietic Stem Cell Emergence in the Zebrafish Dorsal Aorta.
Dev. Cell 2009, 16, 909–916.
Davies, S. G.; Nicholson, R. L.; Price, P. D.; Roberts, P. M.; Russell, A. J.; Savory, E. D.; Smith, A. D. and Thomson, J. E.
Iodine-mediated ring-closing iodoamination with concomitant N-debenzylation for the asymmetric synthesis of polyhydroxylated pyrrolidines.
Tetrahedron: Asymmetry 2009, 20, 758–772.
Pettigrew, D. M.; Roversi, P.; Davies, S. G; Russell, A. J. and Lea, S. M.
Structural studies of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol.
Acta Cryst. D 2009, 65, 513–522
Aciro, C.; Davies, S. G.; Kurosawa, W.; Roberts, P. M.; Russell, A. J. and Thomson, J. E.
Highly diastereoselective anti-dihydroxylation of 3-N,N-dibenzylaminocyclohex-1-ene N-oxide.
Org. Lett. 2009, 11, 1333–1336.
Davies, S. G.; Durbin, M. J; Goddard, E. C.; Kelly, P. M.; Kurosawa, W.; Lee, J. A.; Nicholson, R. L.; Price, P. D.; Roberts, P. M.; Russell, A. J.; Scott, P. M. and Smith, A. D.
Double diastereoselective conjugate addition of homochiral lithium amides to homochiral α,β-unsaturated esters containing cis- and trans-dioxolane units.
Org. Biomol. Chem. 2009, 7, 761–776.
Russell, A. J.; Westwood, I. M.; Crawford, M. C.; Robinson, J.; Kawamura, A.; Redfield, C.; Lowe, E. D.; Laurieri, N.; Davies, S. G. and Sim, E.
Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.
Bioorg. Med. Chem. 2009, 17, 905–918.
Davies, S. G.; Durbin, M. J.; Hartman, S. J. S.; Matsuno, A.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Thomson, J. E. and Toms, S. M.
Parallel kinetic resolution of tert-butyl (RS)-6-alkyl-cyclohex-1-ene-carboxylates for the asymmetric synthesis of 6-alkyl-substituted cishexacin derivatives.
Tetrahedron: Asymmetry 2009, 19, 2870–2881.
Case-Green, S. C.; Davies, S. G.; Roberts, P. M.; Russell, A. J. and Thomson, J. A.
Asymmetric synthesis of tetrahydrolipstatin and valilactone.
Tetrahedron: Asymmetry 2009, 19, 2870–2881.
Lack, N. A.; Kawamura, A.; Fullam, E.; Laurieri, N.; Beard, S.; Russell, A. J.; Evangelopoulos, D.; Westwood I. and Sim, E.
Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis.
Biochem. J. 2009, 418, 369–378.
Torabi Kachoosangi, R.; Musameh, M. M.; Abu-Yousef, I.; Yousef, J. M.; Kanan, S. M.; Xiao, L.; Davies, S. G.; Russell, A. and Compton, R. G.
Carbon Nanotube - Ionic Liquid Composite Sensors and Biosensors.
Anal. Chem. 2009, 81, 435–442.
2008
Claridge, T. D. W.; Davies, S. G.; Lee, J. A.; Nicholson, R. L.; Roberts, P. M.; Russell, A. J.; Smith, A. D. and Toms, S. M.
Highly (E)-Selective Wadsworth-Emmons Reactions Promoted by Methylmagnesium Bromide.
Org. Lett. 2008, 10, 5437–5440.
Claridge, T. D. W.; Davies, S. G.; Polywka, M. E. C.; Roberts, P. M.; Russell, A. J.; Savory, E. D. and Smith, A. D.
“Pure by NMR?”
Org. Lett. 2008, 10, 5433–5436.
Aciro, C.; Davies, S. G.; Roberts, P. M.; Russell, A. J.; Smith, A. D. and Thomson, J. E.
Ammonium directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-amino-cyclohexane-1,2-diol.
Org. Biomol. Chem. 2008, 20, 3762–3770.
Aciro, C.; Claridge, T. D. W.; Davies, S. G.; Roberts, P. M.; Russell, A. J. and Thomson, J. E.
Ammonium directed dihydroxylation of 3-amino-cyclohex-1-enes: development of a metal-free dihydroxylation protocol.
Org. Biomol. Chem. 2008, 20, 3751–3761
Aciro, C.; Davies, S. G.; Garner, A. C.; Ishii, Y.; Key, M. S.; Ling, K. B.; Prasad, R. S.; Roberts, P. M.; Rodriguez-Solla, H.; O’Leary-Steele, C.; Russell, A. J.; Sanganee, H. J.; Savory, E. D.; Smith, A. D. and Thomson, J. E.
Stereoselective functionalisation of SuperQuat enamides: asymmetric synthesis of homochiral 1,2-diols and α-benzyloxy carbonyl compounds.
Tetrahedron 2008, 64, 9320–9344.
Musameh, M. M.; Kachoosangi, R. T.; Xiao, L.; Russell, A. and Compton, R. G.
Ionic liquid-carbon composite glucose biosensor.
Biosensors and Bioelectronics 2008, 24, 87–92.
Abraham, E.; Davies, S. G.; Docherty, A. J.; Ling, K. B.; Roberts, P. M.; Russell, A. J.; Thomson, J. E. and Toms, S. M.
Parallel kinetic resolution of methyl (RS)-5-tris(phenylthio)methyl-cyclopent-1-ene-carboxylate for the asymmetric synthesis of (1R,2S,5S)- and (1S,2R,5R)-5-methyl-cispentacin.
Tetrahedron: Asymmetry 2008, 19, 1356–1362.
Abraham, E.; Davies, S. G.; Roberts, P. M.; Russell, A. J. and Thomson, J. E.
Jaspine B (pachastrissamine) and 2-epi-jaspine B: synthesis and structural assignment.
Tetrahedron: Asymmetry 2008, 19, 1027–1047
Abraham, E.; Brock, E. A.; Candela-Lena, J. I.; Davies, S. G.; Georgiou, M.; Nicholson, R. L.; Perkins, J. H.; Roberts, P. M.; Russell, A. J.; Sánchez-Fernández, E. M.; Scott, P. M.; Smith, A. D. and Thomson, J. E.
Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition.
Org. Biomol. Chem., 2008, 6, 1665–1673.
Davies, S. G.; Mortimer, D. A. B.; Mulvaney, A. W.; Russell, A. J.; Skarphedinsson, H.; Smith A. D. and Vickers, R. J.
An oxidatively-activated safety catch linker for solid phase synthesis.
Org. Biomol. Chem., 2008, 6, 1625–1634.
2007
Abraham, E.; Candela-Lena, J. I.; Davies, S. G.; Georgiou, M.; Nicholson, R. L.; Roberts, P. M.; Russell, A. J.; Sanchez-Fernandez, E. M.; Smith, A. D.; Thomson, J. E.
Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine) and its C(2)-epimer.
Tetrahedron: Asymmetry 2007, 18, 2510–2513.
Rogers, E. I.; Silvester, D. S.; Jones, S. E. W.; Aldous, L.; Hardacre, C.; Russell, A. J.; Davies, S. G.; Compton, R. G.
Electrochemical kinetics of AgAg+ and TMPDTMPD+ in the room-temperature ionic liquid [C(4)mpyrr][NTf2]; toward optimizing reference electrodes for voltammetry in RTILs.
J. Phys. Chem. C 2007, 111, 13957–13966.
Davies, S. G.; Mulvaney, A. W.; Russell, A. J.; Smith, A. D.
Parallel synthesis of homochiral beta-amino acids.
Tetrahedron: Asymmetry 2007, 18, 1554–1566.
Madikane, V. E.; Bhakta, S.; Russell, A. J.; Campbell, W. E.; Claridge, T. D. W.; Elisha, B. G.; Davies, S. G.; Smith, P.; Sim, E.
Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.
Bioorg. Med. Chem. 2007, 15, 3579–3586.
Davies, S. G.; Ling, K. B.; Roberts, P. M.; Russell, A. J.; Thomson, J. E.
Diastereoselective Simmons-Smith cyclopropanations of allylic amines and carbamates.
Chem. Commun. 2007, 39, 4029–4031.
Beddow, J. E.; Davies, S. G.; Ling, K. B.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Thomson, J. E.
Asymmetric synthesis of beta(2)-amino acids: 2-substituted-3-aminopropanoic acids from N-acryloyl SuperQuat derivatives.
Org. Biomol. Chem. 2007, 5, 2812–2825.
Davies, S. G.; Russell, A. J.; Sheppard, R. L.; Smith, A. D.; Thomson, J. E.
Evaluating beta-amino acids as enantioselective organocatalysts of the Hajos-Parrish-Eder-Sauer-Wiechert reaction.
Org. Biomol. Chem. 2007, 5, 3190–3200.
Cailleau, T.; Cooke, J. W. B.; Davies, S. G.; Ling, K. B.; Naylor, A.; Nicholson, R. L.; Price, P. D.; Roberts, P. M.; Russell, A. J.; Smith, A. D.; Thomson, J. E.
Asymmetric synthesis of beta-amino-gamma-substituted-gamma-butyrolactones: double diastereoselective conjugate addition of homochiral lithium amides to homochiral alpha,beta-unsaturated esters.
Org. Biomol. Chem. 2007, 5, 3922–3931.
pre-2007
Davies, S. G.; Garrido, N. M.; Kruchinin, D.; Ichihara, O.; Kotchie, L. J.; Price, P. D.; Mortimer, A. J. P.; Russell, A. J.; Smith, A. D.
Homochiral lithium amides for the asymmetric synthesis of beta-amino acids.
Tetrahedron: Asymmetry 2006, 17, 1793–1811.
Candela-Lena, J. I.; Davies, S. G.; Roberts, P. M.; Roux, B.; Russell, A. J.; Sanchez-Fernandez, E. M.; Smith, A. D.
Asymmetric synthesis of alpha-mercapto-beta-amino acid derivatives: application to the synthesis of polysubstituted thiomorpholines.
Tetrahedron: Asymmetry 2006, 17, 1135–1145.
Westwood, I. M.; Kawamura, A.; Fullam, E.; Russell, A. J.; Davies, S. G.; Sim, E.
Structure and mechanism of arylamine N-acetyltransferases.
Curr. Top. Med. Chem. 2006, 6, 1641–1654.
Book Chapters
Davies, S. G. and Russell, A. J.
Chemical Biology of Stem Cell Modulation
New Frontiers in Chemical Biology, Bunnage, M. E. (Ed.)
Royal Society of Chemistry, 2011, ISBN: 184973125X.
Russell, A. J. and Wynne, G. M.
Drug Discovery Approaches for Rare Neuromuscular Diseases
Orphan Drugs and Rare Diseases, Palmer, M. and Pryde, D. (Ed.)
Royal Society of Chemistry, 2014, ISBN: 978-1-84973-806-4.